日度归档：2024年2月10日

MES缓冲液,一水

发表于由
产品介绍

MES缓冲液,一水，英文名称：MES,FREE ACID,MONOHYDRATE，等级：超纯级，包装规格：50KG，CAS：145224-94-8

MES缓冲液,一水，英文名称：MES,FREE ACID,MONOHYDRATE，等级：超纯级，包装规格：250G分装，CAS：145224-94-8

E169
MES FREE ACID MONOHYDRATE
Grade:ULTRA PURE GRADE
CAS Number: 145224-94-8Synonym(s): 2-(N-morpholino)ethanesulfonic acid
Molecular Weight: 213.2Molecular Formula: C6H13NO4S.H2O
Storage Condition: ROOM TEMPERATURE
CodeSizePriceQuantity
E169-100G
E169-250G
E169-500G
Biological buffers are useful for cell culture in vitro, enzyme assays and some electrophoretic applications at physiological pH. Universally applicable buffers for biochemistry must be water soluble, not interfere with biological processes or biological membranes (penetration, solubilization, adsorption on surface, etc.), have known complex-forming tendency with metal ions, be non-toxic and have a very low U.V. absorption at wavelength >260 nm.

3-吲哚丙酸,现货供应

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英文名称：IPA；3-Indolepropionic acid；Indole-3-propionic acid；3-(1H-Indol-3-yl)propanoic acid
其他名称：氮茚基丙酸；吲哚-3-丙酸；吲哚丙酸；3-（3-吲哚基）丙醇
CAS号：830-96-6
C11H11NO2 =189.21

级别：试剂级
含量：≥99.0%
熔点：132～134℃
性状(以下信息仅供参考)：白色或类白色或淡黄色结晶粉末。易溶于乙醇、乙醚、丙酮、苯、氯仿和乙酸乙酯，溶于热水，难溶于冷水。露置空气中逐渐变色
用途：本品仅供科研，不得用于其它用途
保存：RT，避光保存

PCI 29732

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PCI 29732
分子式：C22H21N5O分子量：371.43

简介： PCI 29732是一种选择性的、不可逆的Btk抑制剂，IC50为0.5 nM。 
物理性状及指标： 
外观：……………………粉末 
溶解性：…………………DMSO: 74 mg/mL  (199.23 mM)；Ethanol：4 mg/mL (10.77 mM)；Water：Insoluble 
含量：……………………>98% 
储存温度：-20℃，避光防潮密闭干燥

生物活性

描述

PCI 29732是一种选择性的、不可逆的Btk抑制剂，IC50为0.5 nM。

靶点

BTK  (Cell-free assay)

BLK  (Cell-free assay)

Bmx  (Cell-free assay)

EGFR  (Cell-free assay)

YES  (Cell-free assay)

 

0.5 nM

0.5 nM

0.8 nM

5.6 nM

6.5 nM

体外

PCI-32765 blocks BCR signaling in human peripheral B cells at concentrations that does not affect T cell receptor signaling. In DOHH2 cells, PCI-32765 inhibits autophosphorylation of Btk (IC50, 11 nM), phosphorylation of Btk’s physiological substrate PLCγ(IC50, 29 nM), and phosphorylation of a further downstream kinase, ERK (IC50, 13 nM). PCI-32765 is more than 1,000-fold selective for inhibition of antigen receptor signaling in B cells over T cells, and that only B-cell inhibition is sustained following short duration treatment.

体内

In mice with collagen-induced arthritis, orally administered PCI-32765 reduces the level of circulating autoantibodies and completely suppresses disease. PCI-32765 also inhibits autoantibody production and the development of kidney disease in the MRL-Fas(lpr) lupus model. The mean terminal plasma half-life of PCI-32765 following oral dosing in mice is 1.7 to 3.1 h.

动物实验

Animal Models: Arthritic DBA/1 mice
Formulation: —
Dosages: 3.125, 12.5, or 50 mg/kg per day
Administration: oral
(Only for Reference)

储液配置及储存： 按表中溶解性配置；如溶解困难，可以通过快速搅拌，超声或温和加热（在45-60°C下水浴）。液体稳定性报道的很少，建议现配现用，如需储存，建议：-20℃1-3月；-80℃ 3-6月。

浓度/体积/质量

1 mg

5 mg

10 mg

1 mM

2.6923 mL

13.4615 mL

26.9230 mL

5 mM

0.5385 mL

2.6923 mL

5.3846 mL

10 mM

0.2692 mL

1.3461 mL

2.6923 mL

50 mM

0.0538 mL

0.2692 mL

0.5385 mL

●我司产品为非无菌包装，若用于细胞培养，请提前做预处理，除去热原细菌，否则会导致染菌。 

●部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，以上数据仅供参考交流研究之用。

我司所售出产品仅供于科研研究用途（非临床科研研究），每次销售产品行为都适用于我司网上所列明的。

CAS 号：330786-25-9
英文名字：PCI 29732
质量标准：>98%,BR
分子式：C22H21N5O

MES缓冲液,一水

发表于由
产品介绍

MES缓冲液,一水，英文名称：MES,FREE ACID,MONOHYDRATE，等级：超纯级，包装规格：500G，CAS：145224-94-8

MES缓冲液,一水，英文名称：MES,FREE ACID,MONOHYDRATE，等级：超纯级，包装规格：250G分装，CAS：145224-94-8

E169
MES FREE ACID MONOHYDRATE
Grade:ULTRA PURE GRADE
CAS Number: 145224-94-8Synonym(s): 2-(N-morpholino)ethanesulfonic acid
Molecular Weight: 213.2Molecular Formula: C6H13NO4S.H2O
Storage Condition: ROOM TEMPERATURE
CodeSizePriceQuantity
E169-100G
E169-250G
E169-500G
Biological buffers are useful for cell culture in vitro, enzyme assays and some electrophoretic applications at physiological pH. Universally applicable buffers for biochemistry must be water soluble, not interfere with biological processes or biological membranes (penetration, solubilization, adsorption on surface, etc.), have known complex-forming tendency with metal ions, be non-toxic and have a very low U.V. absorption at wavelength >260 nm.

3-吲哚乙酸钠,现货供应

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英文名称：IAA-Na；3-Indole butyric acid sodium salt
其他名称：吲哚-3-乙酸钠；吲哚乙酸钠
CAS号：6505-45-9
C10H8NNaO2=197.17
级别：Reagent grade
含量：≥98.0%
水分：≤8.0%
性状(以下信息仅供参考)：白色或类白色结晶性粉末。溶于水
用途：本品仅供科研，不得用于其它用途。(以下用途仅供参考)分析试剂
保存：2～8℃，避光

3-吲哚乙酸,现货供应

发表于由

英文名称：IAA；IUPAC ；3-Indolylacetic acid；1H-Indole-3-acetic acid；Heteroauxin；Indole-3-acetic acid
其他名称：吲哚-3-乙酸；氮茚基乙酸；杂茁长素；吲哚乙酸；β-吲哚乙酸；2-(3-吲哚基)乙酸；生长素；3-吲哚醋酸
CAS号：87-51-4
C10H9NO2=175.19
级别：Reagent grade
含量：≥99.0%
熔点：166～169℃
干燥失重：≤0.50%
性状(以下信息仅供参考)：白色或类白色结晶性粉末。易溶于丙酮和乙醚，微溶于氯仿，不溶于水。
用途：本品仅供科研，不得用于其它用途。
保存：RT，避光

MES缓冲液,一水

发表于由
产品介绍

MES缓冲液,一水，英文名称：MES,FREE ACID,MONOHYDRATE，等级：超纯级，包装规格：25G分装，CAS：145224-94-8

MES缓冲液,一水，英文名称：MES,FREE ACID,MONOHYDRATE，等级：超纯级，包装规格：250G分装，CAS：145224-94-8

E169
MES FREE ACID MONOHYDRATE
Grade:ULTRA PURE GRADE
CAS Number: 145224-94-8Synonym(s): 2-(N-morpholino)ethanesulfonic acid
Molecular Weight: 213.2Molecular Formula: C6H13NO4S.H2O
Storage Condition: ROOM TEMPERATURE
CodeSizePriceQuantity
E169-100G
E169-250G
E169-500G
Biological buffers are useful for cell culture in vitro, enzyme assays and some electrophoretic applications at physiological pH. Universally applicable buffers for biochemistry must be water soluble, not interfere with biological processes or biological membranes (penetration, solubilization, adsorption on surface, etc.), have known complex-forming tendency with metal ions, be non-toxic and have a very low U.V. absorption at wavelength >260 nm.