RNase III Drosha (I-16)

产品介绍

 

sc-31024 K-cadherin (K-13) 200 ug/ml Store at 4° C,
sc-31024 P K-cadherin (K-13) P 100 ug/0.5 ml Store at 4° C,
sc-31025 K-cadherin (E-14) 200 ug/ml Store at 4° C,
sc-31025 P K-cadherin (E-14) P 100 ug/0.5 ml Store at 4° C,
sc-31029 N-cadherin (L-13) 200 ug/ml Store at 4° C,
sc-31029 P N-cadherin (L-13) P 100 ug/0.5 ml Store at 4° C,
sc-31030 N-cadherin (K-20) 200 ug/ml Store at 4° C,
sc-31030 P N-cadherin (K-20) P 100 ug/0.5 ml Store at 4° C,
sc-31031 N-cadherin (C-16) 200 ug/ml Store at 4° C,
sc-31031 P N-cadherin (C-16) P 100 ug/0.5 ml Store at 4° C,
sc-31032 NCAM-L1 (N-14) 200 ug/ml Store at 4° C,
sc-31032 P NCAM-L1 (N-14) P 100 ug/0.5 ml Store at 4° C,
sc-31034 NCAM-L1 (I-18) 200 ug/ml Store at 4° C,
sc-31034 P NCAM-L1 (I-18) P 100 ug/0.5 ml Store at 4° C,
sc-31039 DNAM-1 (Y-15) 200 ug/ml Store at 4° C,
sc-31039 P DNAM-1 (Y-15) P 100 ug/0.5 ml Store at 4° C,
sc-31048 VCAM-1 (D-20) 200 ug/ml Store at 4° C,
sc-31048 P VCAM-1 (D-20) P 100 ug/0.5 ml Store at 4° C,
sc-31050 ICAM-2 (K-20) 200 ug/ml Store at 4° C,
sc-31050 P ICAM-2 (K-20) P 100 ug/0.5 ml Store at 4° C,
sc-31052 PDE2A (V-18) 200 ug/ml Store at 4° C,
sc-31052 P PDE2A (V-18) P 100 ug/0.5 ml Store at 4° C,
sc-31056 TrxR1 (T-16) 200 ug/ml Store at 4° C,
sc-31056 P TrxR1 (T-16) P 100 ug/0.5 ml Store at 4° C,
sc-31057 TrxR1 (L-17) 200 ug/ml Store at 4° C,
sc-31057 P TrxR1 (L-17) P 100 ug/0.5 ml Store at 4° C,
sc-31058 PIN (A-12) 200 ug/ml Store at 4° C,
sc-31058 P PIN (A-12) P 100 ug/0.5 ml Store at 4° C,
sc-31060 frizzled-7 (G-13) 200 ug/ml Store at 4° C,
sc-31060 P frizzled-7 (G-13) P 100 ug/0.5 ml Store at 4° C,
sc-31061 frizzled-7 (D-13) 200 ug/ml Store at 4° C,
sc-31061 P frizzled-7 (D-13) P 100 ug/0.5 ml Store at 4° C,
sc-31063 frizzled-7 (F-13) 200 ug/ml Store at 4° C,
sc-31063 P frizzled-7 (F-13) P 100 ug/0.5 ml Store at 4° C,
sc-31066 Calpain 1 (L-18) 200 ug/ml Store at 4° C,
sc-31066 P Calpain 1 (L-18) P 100 ug/0.5 ml Store at 4° C,
sc-31068 Calpain 3 (G-20) 200 ug/ml Store at 4° C,
sc-31068 P Calpain 3 (G-20) P 100 ug/0.5 ml Store at 4° C,
sc-31073 MMP-3 (V-13) 200 ug/ml Store at 4° C,
sc-31073 P MMP-3 (V-13) P 100 ug/0.5 ml Store at 4° C,
sc-31074 MMP-3 (Y-16) 200 ug/ml Store at 4° C,
sc-31074 P MMP-3 (Y-16) P 100 ug/0.5 ml Store at 4° C,
sc-31080 ADAMTS-1 (L-16) 200 ug/ml Store at 4° C,
sc-31080 P ADAMTS-1 (L-16) P 100 ug/0.5 ml Store at 4° C,
sc-31085 cyclin A  (V-18) 200 ug/ml Store at 4° C,
sc-31085 P cyclin A  (V-18) P 100 ug/0.5 ml Store at 4° C,
sc-31086 cyclin A  (D-19) 200 ug/ml Store at 4° C,
sc-31086 P cyclin A  (D-19) P 100 ug/0.5 ml Store at 4° C,
sc-31092 Laminin ©-2 (G-16) 200 ug/ml Store at 4° C,
sc-31092 P Laminin ©-2 (G-16) P 100 ug/0.5 ml Store at 4° C,
sc-31094 Laminin ©-1 (K-19) 200 ug/ml Store at 4° C,
sc-31094 P Laminin ©-1 (K-19) P 100 ug/0.5 ml Store at 4° C,
sc-31096 CD97 (E-17) 200 ug/ml Store at 4° C,
sc-31096 P CD97 (E-17) P 100 ug/0.5 ml Store at 4° C,
sc-31100 BUB1 (Y-18) 200 ug/ml Store at 4° C,
sc-31100 P BUB1 (Y-18) P 100 ug/0.5 ml Store at 4° C,
sc-31101 BUB1 (E-20) 200 ug/ml Store at 4° C,
sc-31101 P BUB1 (E-20) P 100 ug/0.5 ml Store at 4° C,
sc-31102 p35 (A-18) 200 ug/ml Store at 4° C,
sc-31102 P p35 (A-18) P 100 ug/0.5 ml Store at 4° C,
sc-31103 p35 (S-17) 200 ug/ml Store at 4° C,
sc-31103 P p35 (S-17) P 100 ug/0.5 ml Store at 4° C,
sc-31109 Hemoglobin a (V-13) 200 ug/ml Store at 4° C,
sc-31109 P Hemoglobin a (V-13) P 100 ug/0.5 ml Store at 4° C,
sc-31110 Hemoglobin a (D-16) 200 ug/ml Store at 4° C,
sc-31110 P Hemoglobin a (D-16) P 100 ug/0.5 ml Store at 4° C,
sc-31111 Hemoglobin a (A-17) 200 ug/ml Store at 4° C,
sc-31111 P Hemoglobin a (A-17) P 100 ug/0.5 ml Store at 4° C,
sc-31116 Hemoglobin b (M-19) 200 ug/ml Store at 4° C,
sc-31116 P Hemoglobin b (M-19) P 100 ug/0.5 ml Store at 4° C,
sc-31117 Hemoglobin g (N-15) 200 ug/ml Store at 4° C,
sc-31117 P Hemoglobin g (N-15) P 100 ug/0.5 ml Store at 4° C,
sc-31125 CyPB (G-13) 200 ug/ml Store at 4° C,
sc-31125 P CyPB (G-13) P 100 ug/0.5 ml Store at 4° C,
sc-31131 FANCA (P-15) 200 ug/ml Store at 4° C,
sc-31131 P FANCA (P-15) P 100 ug/0.5 ml Store at 4° C,
sc-31138 cyclin G2 (L-20) 200 ug/ml Store at 4° C,
sc-31138 P cyclin G2 (L-20) P 100 ug/0.5 ml Store at 4° C,
sc-31142 PMS1 (L-19) 200 ug/ml Store at 4° C,
sc-31142 P PMS1 (L-19) P 100 ug/0.5 ml Store at 4° C,
sc-31143 PMS1 (I-16) 200 ug/ml Store at 4° C,
sc-31143 P PMS1 (I-16) P 100 ug/0.5 ml Store at 4° C,
sc-31151 ErbB-4 (T-18) 200 ug/ml Store at 4° C,
sc-31151 P ErbB-4 (T-18) P 100 ug/0.5 ml Store at 4° C,
sc-31153 Neu (D-16) 200 ug/ml Store at 4° C,
sc-31153 P Neu (D-16) P 100 ug/0.5 ml Store at 4° C,
sc-31154 Neu (C-14) 200 ug/ml Store at 4° C,
sc-31154 P Neu (C-14) P 100 ug/0.5 ml Store at 4° C,
sc-31156 EGFR (D-20) 200 ug/ml Store at 4° C,
sc-31156 P EGFR (D-20) P 100 ug/0.5 ml Store at 4° C,
sc-31157 EGFR (C-20) 200 ug/ml Store at 4° C,
sc-31157 P EGFR (C-20) P 100 ug/0.5 ml Store at 4° C,
sc-31158 RNase III Drosha (I-16) 200 ug/ml Store at 4° C,
sc-31158 P RNase III Drosha (I-16) P 100 ug/0.5 ml Store at 4° C,
sc-31159 RNase III Drosha (E-19) 200 ug/ml Store at 4° C,
sc-31159 P RNase III Drosha (E-19) P 100 ug/0.5 ml Store at 4° C,
sc-31162 FGFR-3 (P-18) 200 ug/ml Store at 4° C,
sc-31162 P FGFR-3 (P-18) P 100 ug/0.5 ml Store at 4° C,
sc-31163 FGFR-3 (L-14) 200 ug/ml Store at 4° C,
sc-31163 P FGFR-3 (L-14) P 100 ug/0.5 ml Store at 4° C,

talin (H-18)

产品介绍

 

sc-30873 P Dvl-2 (F-13) P 100 ug/0.5 ml Store at 4° C,
sc-30875 PIASy (P-18) 200 ug/ml Store at 4° C,
sc-30875 P PIASy (P-18) P 100 ug/0.5 ml Store at 4° C,
sc-30876 PIASy (I-19) 200 ug/ml Store at 4° C,
sc-30876 P PIASy (I-19) P 100 ug/0.5 ml Store at 4° C,
sc-30878 PIASx (L-19) 200 ug/ml Store at 4° C,
sc-30878 P PIASx (L-19) P 100 ug/0.5 ml Store at 4° C,
sc-30879 PIASx (S-15) 200 ug/ml Store at 4° C,
sc-30879 P PIASx (S-15) P 100 ug/0.5 ml Store at 4° C,
sc-30882 eIF2å (K-17) 200 ug/ml Store at 4° C,
sc-30882 P eIF2å (K-17) P 100 ug/0.5 ml Store at 4° C,
sc-30883 Syndecan-3 (V-14) 200 ug/ml Store at 4° C,
sc-30883 P Syndecan-3 (V-14) P 100 ug/0.5 ml Store at 4° C,
sc-30884 Syndecan-3 (T-20) 200 ug/ml Store at 4° C,
sc-30884 P Syndecan-3 (T-20) P 100 ug/0.5 ml Store at 4° C,
sc-30886 Syndecan-3 (A-16) 200 ug/ml Store at 4° C,
sc-30886 P Syndecan-3 (A-16) P 100 ug/0.5 ml Store at 4° C,
sc-30887 RelB (N-17) 200 ug/ml Store at 4° C,
sc-30887 P RelB (N-17) P 100 ug/0.5 ml Store at 4° C,
sc-30888 RelB (K-20) 200 ug/ml Store at 4° C,
sc-30888 P RelB (K-20) P 100 ug/0.5 ml Store at 4° C,
sc-30890 EFP (S-16) 200 ug/ml Store at 4° C,
sc-30890 P EFP (S-16) P 100 ug/0.5 ml Store at 4° C,
sc-30890 X EFP (S-16) X 200 ug/0.1 ml Store at 4° C,
sc-30893 IRF-2 (H-17) 200 ug/ml Store at 4° C,
sc-30893 P IRF-2 (H-17) P 100 ug/0.5 ml Store at 4° C,
sc-30894 IRF-2 (G-20) 200 ug/ml Store at 4° C,
sc-30894 P IRF-2 (G-20) P 100 ug/0.5 ml Store at 4° C,
sc-30898 USF-1 (C-15) 200 ug/ml Store at 4° C,
sc-30898 P USF-1 (C-15) P 100 ug/0.5 ml Store at 4° C,
sc-30900 USF-2 (A-19) 200 ug/ml Store at 4° C,
sc-30900 P USF-2 (A-19) P 100 ug/0.5 ml Store at 4° C,
sc-30901 USF-2 (C-13) 200 ug/ml Store at 4° C,
sc-30901 P USF-2 (C-13) P 100 ug/0.5 ml Store at 4° C,
sc-30903 CBF-A (E-20) 200 ug/ml Store at 4° C,
sc-30903 P CBF-A (E-20) P 100 ug/0.5 ml Store at 4° C,
sc-30906 CBF-B (Y-12) 200 ug/ml Store at 4° C,
sc-30906 P CBF-B (Y-12) P 100 ug/0.5 ml Store at 4° C,
sc-30908 A-Myb (T-14) 200 ug/ml Store at 4° C,
sc-30908 P A-Myb (T-14) P 100 ug/0.5 ml Store at 4° C,
sc-30909 A-Myb (P-18) 200 ug/ml Store at 4° C,
sc-30909 P A-Myb (P-18) P 100 ug/0.5 ml Store at 4° C,
sc-30911 Nrf1 (G-20) 200 ug/ml Store at 4° C,
sc-30911 P Nrf1 (G-20) P 100 ug/0.5 ml Store at 4° C,
sc-30915 Nrf2 (T-19) 200 ug/ml Store at 4° C,
sc-30915 P Nrf2 (T-19) P 100 ug/0.5 ml Store at 4° C,
sc-30923 NG2 (G-20) 200 ug/ml Store at 4° C,
sc-30923 P NG2 (G-20) P 100 ug/0.5 ml Store at 4° C,
sc-30927 CPI-17 (A-20) 200 ug/ml Store at 4° C,
sc-30927 P CPI-17 (A-20) P 100 ug/0.5 ml Store at 4° C,
sc-30930 CPI-17 (K-20) 200 ug/ml Store at 4° C,
sc-30930 P CPI-17 (K-20) P 100 ug/0.5 ml Store at 4° C,
sc-30932 PDI (H-17) 200 ug/ml Store at 4° C,
sc-30932 P PDI (H-17) P 100 ug/0.5 ml Store at 4° C,
sc-30934 ∫-defensin 3 (K-13) 200 ug/ml Store at 4° C,
sc-30934 P ∫-defensin 3 (K-13) P 100 ug/0.5 ml Store at 4° C,
sc-30938 ∫-Arrestin-2 (D-18) 200 ug/ml Store at 4° C,
sc-30938 P ∫-Arrestin-2 (D-18) P 100 ug/0.5 ml Store at 4° C,
sc-30943 Bmi-1 (S-15) 200 ug/ml Store at 4° C,
sc-30943 P Bmi-1 (S-15) P 100 ug/0.5 ml Store at 4° C,
sc-30944 Bmi-1 (K-18) 200 ug/ml Store at 4° C,
sc-30944 P Bmi-1 (K-18) P 100 ug/0.5 ml Store at 4° C,
sc-30957 ORC3 (G-20) 200 ug/ml Store at 4° C,
sc-30957 P ORC3 (G-20) P 100 ug/0.5 ml Store at 4° C,
sc-30962 mtTFA (A-16) 200 ug/ml Store at 4° C,
sc-30962 P mtTFA (A-16) P 100 ug/0.5 ml Store at 4° C,
sc-30963 mtTFA (E-16) 200 ug/ml Store at 4° C,
sc-30963 P mtTFA (E-16) P 100 ug/0.5 ml Store at 4° C,
sc-30968 ARA70 (Q-19) 200 ug/ml Store at 4° C,
sc-30968 P ARA70 (Q-19) P 100 ug/0.5 ml Store at 4° C,
sc-30971 Hic-5 (P-19) 200 ug/ml Store at 4° C,
sc-30971 P Hic-5 (P-19) P 100 ug/0.5 ml Store at 4° C,
sc-30972 Hic-5 (D-15) 200 ug/ml Store at 4° C,
sc-30972 P Hic-5 (D-15) P 100 ug/0.5 ml Store at 4° C,
sc-30974 Laminin ∫-2 (N-20) 200 ug/ml Store at 4° C,
sc-30974 P Laminin ∫-2 (N-20) P 100 ug/0.5 ml Store at 4° C,
sc-30975 Laminin ∫-2 (A-16) 200 ug/ml Store at 4° C,
sc-30975 P Laminin ∫-2 (A-16) P 100 ug/0.5 ml Store at 4° C,
sc-30976 Laminin ∫-2 (K-20) 200 ug/ml Store at 4° C,
sc-30976 P Laminin ∫-2 (K-20) P 100 ug/0.5 ml Store at 4° C,
sc-30977 Vitronectin 75 (N-20) 200 ug/ml Store at 4° C,
sc-30977 P Vitronectin 75 (N-20) P 100 ug/0.5 ml Store at 4° C,
sc-30982 connexin 32 (E-17) 200 ug/ml Store at 4° C,
sc-30982 P connexin 32 (E-17) P 100 ug/0.5 ml Store at 4° C,
sc-30986 Integrin å2 (A-18) 200 ug/ml Store at 4° C,
sc-30986 P Integrin å2 (A-18) P 100 ug/0.5 ml Store at 4° C,
sc-30988 Integrin å2 (K-14) 200 ug/ml Store at 4° C,
sc-30988 P Integrin å2 (K-14) P 100 ug/0.5 ml Store at 4° C,
sc-30990 claudin-11 (I-18) 200 ug/ml Store at 4° C,
sc-30990 P claudin-11 (I-18) P 100 ug/0.5 ml Store at 4° C,
sc-30997 ©-catenin (K-20) 200 ug/ml Store at 4° C,
sc-30997 P ©-catenin (K-20) P 100 ug/0.5 ml Store at 4° C,
sc-31001 ∫-catenin (E-17) 200 ug/ml Store at 4° C,
sc-31001 P ∫-catenin (E-17) P 100 ug/0.5 ml Store at 4° C,
sc-31002 å E-catenin (L-15) 200 ug/ml Store at 4° C,
sc-31002 P å E-catenin (L-15) P 100 ug/0.5 ml Store at 4° C,
sc-31007 å N-catenin (I-17) 200 ug/ml Store at 4° C,
sc-31007 P å N-catenin (I-17) P 100 ug/0.5 ml Store at 4° C,
sc-31012 talin (H-18) 200 ug/ml Store at 4° C,
sc-31012 P talin (H-18) P 100 ug/0.5 ml Store at 4° C,

TMEFF1 (C-16) P

产品介绍

 

sc-30767 P Annexin VIII (R-18) P 100 ug/0.5 ml Store at 4° C,
sc-30770 Cortactin (F-14) 200 ug/ml Store at 4° C,
sc-30770 P Cortactin (F-14) P 100 ug/0.5 ml Store at 4° C,
sc-30771 Cortactin (G-18) 200 ug/ml Store at 4° C,
sc-30771 P Cortactin (G-18) P 100 ug/0.5 ml Store at 4° C,
sc-30773 Wnt-2 (G-15) 200 ug/ml Store at 4° C,
sc-30773 P Wnt-2 (G-15) P 100 ug/0.5 ml Store at 4° C,
sc-30778 Eps8 (C-19) 200 ug/ml Store at 4° C,
sc-30778 P Eps8 (C-19) P 100 ug/0.5 ml Store at 4° C,
sc-30781 FTb (C-20) 200 ug/ml Store at 4° C,
sc-30781 P FTb (C-20) P 100 ug/0.5 ml Store at 4° C,
sc-30782 Dkk-1 (S-20) 200 ug/ml Store at 4° C,
sc-30782 P Dkk-1 (S-20) P 100 ug/0.5 ml Store at 4° C,
sc-30785 Dkk-1 (G-18) 200 ug/ml Store at 4° C,
sc-30785 P Dkk-1 (G-18) P 100 ug/0.5 ml Store at 4° C,
sc-30786 Dkk-2 (E-15) 200 ug/ml Store at 4° C,
sc-30786 P Dkk-2 (E-15) P 100 ug/0.5 ml Store at 4° C,
sc-30787 Dkk-2 (T-20) 200 ug/ml Store at 4° C,
sc-30787 P Dkk-2 (T-20) P 100 ug/0.5 ml Store at 4° C,
sc-30791 WIF-1 (K-16) 200 ug/ml Store at 4° C,
sc-30791 P WIF-1 (K-16) P 100 ug/0.5 ml Store at 4° C,
sc-30792 WIF-1 (M-16) 200 ug/ml Store at 4° C,
sc-30792 P WIF-1 (M-16) P 100 ug/0.5 ml Store at 4° C,
sc-30793 PKCg (N-16) 200 ug/ml Store at 4° C,
sc-30793 P PKCg (N-16) P 100 ug/0.5 ml Store at 4° C,
sc-30797 LAR (E-20) 200 ug/ml Store at 4° C,
sc-30797 P LAR (E-20) P 100 ug/0.5 ml Store at 4° C,
sc-30799 LAR (T-15) 200 ug/ml Store at 4° C,
sc-30799 P LAR (T-15) P 100 ug/0.5 ml Store at 4° C,
sc-30804 PTPk (E-18) 200 ug/ml Store at 4° C,
sc-30804 P PTPk (E-18) P 100 ug/0.5 ml Store at 4° C,
sc-30806 PTPk (G-12) 200 ug/ml Store at 4° C,
sc-30806 P PTPk (G-12) P 100 ug/0.5 ml Store at 4° C,
sc-30810 SH-PTP1 (G-20) 200 ug/ml Store at 4° C,
sc-30810 P SH-PTP1 (G-20) P 100 ug/0.5 ml Store at 4° C,
sc-30814 THOC4 (S-17) 200 ug/ml Store at 4° C,
sc-30814 P THOC4 (S-17) P 100 ug/0.5 ml Store at 4° C,
sc-30816 THOC4 (Q-15) 200 ug/ml Store at 4° C,
sc-30816 P THOC4 (Q-15) P 100 ug/0.5 ml Store at 4° C,
sc-30818 PSF (K-18) 200 ug/ml Store at 4° C,
sc-30818 P PSF (K-18) P 100 ug/0.5 ml Store at 4° C,
sc-30820 3∫-HSD (P-18) 200 ug/ml Store at 4° C,
sc-30820 P 3∫-HSD (P-18) P 100 ug/0.5 ml Store at 4° C,
sc-30821 3∫-HSD (C-18) 200 ug/ml Store at 4° C,
sc-30821 P 3∫-HSD (C-18) P 100 ug/0.5 ml Store at 4° C,
sc-30823 CRALBP (L-19) 200 ug/ml Store at 4° C,
sc-30823 P CRALBP (L-19) P 100 ug/0.5 ml Store at 4° C,
sc-30825 PLC ∂3 (H-14) 200 ug/ml Store at 4° C,
sc-30825 P PLC ∂3 (H-14) P 100 ug/0.5 ml Store at 4° C,
sc-30826 PLC ∂3 (L-15) 200 ug/ml Store at 4° C,
sc-30826 P PLC ∂3 (L-15) P 100 ug/0.5 ml Store at 4° C,
sc-30830 PLC ∂4 (Q-15) 200 ug/ml Store at 4° C,
sc-30830 P PLC ∂4 (Q-15) P 100 ug/0.5 ml Store at 4° C,
sc-30832 TRAP (N-17) 200 ug/ml Store at 4° C,
sc-30832 P TRAP (N-17) P 100 ug/0.5 ml Store at 4° C,
sc-30833 TRAP (K-17) 200 ug/ml Store at 4° C,
sc-30833 P TRAP (K-17) P 100 ug/0.5 ml Store at 4° C,
sc-30835 PLTP (N-17) 200 ug/ml Store at 4° C,
sc-30835 P PLTP (N-17) P 100 ug/0.5 ml Store at 4° C,
sc-30838 UFD2 (N-16) 200 ug/ml Store at 4° C,
sc-30838 P UFD2 (N-16) P 100 ug/0.5 ml Store at 4° C,
sc-30841 NMNAT-1 (N-17) 200 ug/ml Store at 4° C,
sc-30841 P NMNAT-1 (N-17) P 100 ug/0.5 ml Store at 4° C,
sc-30842 NMNAT-1 (D-20) 200 ug/ml Store at 4° C,
sc-30842 P NMNAT-1 (D-20) P 100 ug/0.5 ml Store at 4° C,
sc-30844 ∫-glucosidase (N-17) 200 ug/ml Store at 4° C,
sc-30844 P ∫-glucosidase (N-17) P 100 ug/0.5 ml Store at 4° C,
sc-30845 ∫-glucosidase (L-17) 200 ug/ml Store at 4° C,
sc-30845 P ∫-glucosidase (L-17) P 100 ug/0.5 ml Store at 4° C,
sc-30847 LEKTI (N-15) 200 ug/ml Store at 4° C,
sc-30847 P LEKTI (N-15) P 100 ug/0.5 ml Store at 4° C,
sc-30849 LEKTI (L-16) 200 ug/ml Store at 4° C,
sc-30849 P LEKTI (L-16) P 100 ug/0.5 ml Store at 4° C,
sc-30850 LEKTI (S-13) 200 ug/ml Store at 4° C,
sc-30850 P LEKTI (S-13) P 100 ug/0.5 ml Store at 4° C,
sc-30854 Mig-2 (Y-15) 200 ug/ml Store at 4° C,
sc-30854 P Mig-2 (Y-15) P 100 ug/0.5 ml Store at 4° C,
sc-30856 ATP7A (N-15) 200 ug/ml Store at 4° C,
sc-30856 P ATP7A (N-15) P 100 ug/0.5 ml Store at 4° C,
sc-30858 ATP7A (C-20) 200 ug/ml Store at 4° C,
sc-30858 P ATP7A (C-20) P 100 ug/0.5 ml Store at 4° C,
sc-30859 GP-39 (E-15) 200 ug/ml Store at 4° C,
sc-30859 P GP-39 (E-15) P 100 ug/0.5 ml Store at 4° C,
sc-30861 GP-39 (M-20) 200 ug/ml Store at 4° C,
sc-30861 P GP-39 (M-20) P 100 ug/0.5 ml Store at 4° C,
sc-30862 TMEFF1 (K-18) 200 ug/ml Store at 4° C,
sc-30862 P TMEFF1 (K-18) P 100 ug/0.5 ml Store at 4° C,
sc-30864 TMEFF1 (C-16) 200 ug/ml Store at 4° C,
sc-30864 P TMEFF1 (C-16) P 100 ug/0.5 ml Store at 4° C,
sc-30867 SPT3 (C-20) 200 ug/ml Store at 4° C,
sc-30867 P SPT3 (C-20) P 100 ug/0.5 ml Store at 4° C,
sc-30869 Fgl2 (S-20) 200 ug/ml Store at 4° C,
sc-30869 P Fgl2 (S-20) P 100 ug/0.5 ml Store at 4° C,
sc-30870 Fgl2 (K-17) 200 ug/ml Store at 4° C,
sc-30870 P Fgl2 (K-17) P 100 ug/0.5 ml Store at 4° C,
sc-30871 Dvl-2 (I-20) 200 ug/ml Store at 4° C,
sc-30871 P Dvl-2 (I-20) P 100 ug/0.5 ml Store at 4° C,
sc-30872 Dvl-2 (E-15) 200 ug/ml Store at 4° C,
sc-30872 P Dvl-2 (E-15) P 100 ug/0.5 ml Store at 4° C,
sc-30873 Dvl-2 (F-13) 200 ug/ml Store at 4° C,

Regorafenib(BAY 73-4506)

Regorafenib(BAY 73-4506);瑞格非尼(BAY 73-4506)        
分子式:C21H15ClF4N4O3 分子量:482.81

简介: Regorafenib (BAY 73-4506) 是一种多靶点受体酪氨酸激酶抑制剂,抑制VEGFR1/2/3,PDGFRβ,Kit,RET 和 Raf-1。 

别名:瑞戈非尼 ;BAY 73-4506;2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3- fluorophenoxy]-N-methyl
物理性状及指标:
外观:………………白色至棕色固体
溶解性:……………DMSO:97 mg/mL (200.9 mM);Water Insoluble;Ethanol Insoluble
含量:………………>99%

储存条件: -20℃,避光防潮密闭干燥 

运输条件:2~8℃运输
生物活性

产品描述

Regorafenib 是一个多激酶抑制剂,靶点有VEGFR1, 鼠的 VEGFR2, 鼠的VEGF3, PDGFR-β, KIT, RET 和 RAF-1 ,IC50 分别是 13 nM, 4.2 nM, 46 nM, 22 nM, 7 nM, 1.5 nM 和 2.5 nM。

靶点

VEGFR1

鼠源 VEGFR2

鼠源 VEGF3

PDGFR-β

KIT

IC50

13 Nm

4.2 nM

46 nM

22 nM

7 nM

体外研究

在 NIH-3T3细胞中 Regorafenib 强烈抑制 VEGFR2的 自磷酸化, IC50 为3 nM.在HAoSMCs中, Regorafenib 抑制 PDGFR-β经过PDGF-BB刺激后的自磷酸化, IC50为90 nM. 在MCF-7 乳腺癌细胞中, Regorafenib 也会抑制FGF10刺激后 FGFR 的信号传导. Regorafenib 非常有效的抑制KITK642E 和 RETC634W这两个突变的受体, IC50 分别是大约 20 nM 和 10 nM。 Regorafenib 抑制经过VEGF165 刺激后的HUVECs细胞的增值, IC50 为 大约 3 nM. Regorafenib抑制 FGF2刺激后的 HUVECs和PDGF-BB刺激后的HAoSMCs细胞的增殖, IC50分别是127 nM 和 146 nM。Regorafenib通过抑制酪氨酸激酶受体(VEGFR, KIT, RET, FGFR和 PDGFR)和丝氨酸/ 苏氨酸激酶受体(RAF 和 p38MAPK)来靶向作用于肿瘤细胞增殖和肿瘤脉管系统。Regorafenib以浓度依赖和时间依赖方式抑制 人Hep3B, PLC/PRF/5 和 HepG2细胞的生长。

体内研究

在多种临床前人类异种移植的小鼠模型上, Regorafenib有着很好的肿瘤生长抑制性,这种抑制具有剂量依赖特性, 表现为在乳腺 MDA-MB-231 和 肾脏 786-O 肿瘤模型中肿瘤减小. Regorafenib 不仅阻止了同源主要的 4T1乳腺肿瘤在脂肪垫中的原位生长,也抑制了肿瘤转移到肺部。

特征

Regorafenib是一个新的口服多激酶抑制剂。

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用途及描述 :科研试剂,广泛应用于分子生物学,药理学等科研方面,严禁用于人体。Regorafenib (BAY 73-4506) 是一种多靶点受体酪氨酸激酶抑制剂,抑制VEGFR1/2/3,PDGFRβ,Kit,RET 和 Raf-1。本品可用于相关领域的科研实验。
储液配置

Regorafenib(BAY 73-4506)

1 mg

5 mg

10 mg

1 mM

2.0712 mL

10.3558 mL

20.7117 mL

5 mM

0.4142 mL

2.0712 mL

4.1423 mL

10 mM

0.2071 mL

1.0356 mL

2.0712 mL

50 mM

0.0414 mL

0.2071 mL

0.4142 mL

经典实验操作(仅供参考)

激酶实验

激酶活性测定:
体外激酶实验用重组的VEGFR2 (鼠源, aa785–aa1367), VEGFR3 (鼠源 aa818–aa1363), PDGFR-β (aa561–aa1106), RAF-1 (aa305–aa648) 和 BRAFV600E (aa409–aa765)的激酶活性区域进行。初始的激酶抑制反应将Regorafenib的浓度固定为1 μM. IC50的值根据选定的相应的激酶来测定, 如VEGFR1 和 RET. TIE2 的激酶抑制效果采用均相时间分辨荧光分析法测定,利用重组的TIE2细胞内区域的GST融合蛋白和生物素化的-Ahx-EPKDDAYPLYSDFG多肽作为底物。

细胞实验

  • Cell lines: GIST 882 和 TT 细胞
  • Concentrations: 5 nM-10 μM
  • Incubation Time: 96 小时
  • Method: 为了分析细胞增殖情况, 将GIST 882 和 TT 细胞培养在含有L-glutamine谷氨酸的RPMI 培养基中,MDA-MB-231, HepG2和A375 细胞培养在含有10% hiFBS 的 DMEM 培养基中。将细胞用胰酶消化, 按5× 104 个每孔接种在96孔板中并在含有10% FBS 的完全培养基中37°C培养过夜。第二天, 将对照和Regorafenib用培养基稀释成从10 μM 到5 nM的连续终浓度, 加入 0.2% DMSO,加入细胞培养基中并继续培养96小时。将细胞增殖情况进行量化。

动物实验

  • Animal Models: 携带Colo-205, MDA-MB-231 细胞或者 786-O肿瘤的雌性无胸腺NCr nu/nu 小鼠
  • Formulation: 聚乙二醇400/125 mM 甲磺酸水溶液 (80/20) 或者聚丙烯 乙二醇/聚乙二醇400/Pluronic F68 (42.5/42.5/15 + 20% 水溶液)
  • Dosages: 3 mg/kg, 10 mg/kg, 30 mg/kg, 100 mg/kg
  • Administration: 口服

【注意 】
●我司产品为非无菌包装,若用于细胞培养,请提前做预处理,除去热原细菌,否则会导致染菌。
●部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,以上数据仅供参考交流研究之用。

我司所售出产品仅供于科研研究用途(非临床科研研究),每次销售产品行为都适用于我司网上所列明的

CAS 号:755037-03-7

英文名字:瑞格非尼(BAY 73-4506)
质量标准:>99%,多激酶抑制剂
分子式:C21H15ClF4N4O3
·

·

MYH (M-15) P

产品介绍

 

sc-30515 TCP-1 é  (A-16) 200 ug/ml Store at 4° C,
sc-30515 P TCP-1 é  (A-16) P 100 ug/0.5 ml Store at 4° C,
sc-30517 Ankyrin B (D-20) 200 ug/ml Store at 4° C,
sc-30517 P Ankyrin B (D-20) P 100 ug/0.5 ml Store at 4° C,
sc-30521 Profilin-1 (V-17) 200 ug/ml Store at 4° C,
sc-30521 P Profilin-1 (V-17) P 100 ug/0.5 ml Store at 4° C,
sc-30522 Profilin-1 (C-15) 200 ug/ml Store at 4° C,
sc-30522 P Profilin-1 (C-15) P 100 ug/0.5 ml Store at 4° C,
sc-30531 MAP-1A (V-21) 200 ug/ml Store at 4° C,
sc-30531 P MAP-1A (V-21) P 100 ug/0.5 ml Store at 4° C,
sc-30532 MAP-1A (G-20) 200 ug/ml Store at 4° C,
sc-30532 P MAP-1A (G-20) P 100 ug/0.5 ml Store at 4° C,
sc-30537 ATP-citrate synthase (G-17) 200 ug/ml Store at 4° C,
sc-30537 P ATP-citrate synthase (G-17) P 100 ug/0.5 ml Store at 4° C,
sc-30538 ATP-citrate synthase (C-20) 200 ug/ml Store at 4° C,
sc-30538 P ATP-citrate synthase (C-20) P 100 ug/0.5 ml Store at 4° C,
sc-30540 p107 (D-14) 200 ug/ml Store at 4° C,
sc-30540 P p107 (D-14) P 100 ug/0.5 ml Store at 4° C,
sc-30542 Hus1 (S-21) 200 ug/ml Store at 4° C,
sc-30542 P Hus1 (S-21) P 100 ug/0.5 ml Store at 4° C,
sc-30543 Hus1 (E-21) 200 ug/ml Store at 4° C,
sc-30543 P Hus1 (E-21) P 100 ug/0.5 ml Store at 4° C,
sc-30545 p14 ARF (A-15) 200 ug/ml Store at 4° C,
sc-30545 P p14 ARF (A-15) P 100 ug/0.5 ml Store at 4° C,
sc-30551 NBK (G-20) 200 ug/ml Store at 4° C,
sc-30551 P NBK (G-20) P 100 ug/0.5 ml Store at 4° C,
sc-30552 NBK (E-20) 200 ug/ml Store at 4° C,
sc-30552 P NBK (E-20) P 100 ug/0.5 ml Store at 4° C,
sc-30554 Slk19p (yN-12) 200 ug/ml Store at 4° C,
sc-30554 P Slk19p (yN-12) P 100 ug/0.5 ml Store at 4° C,
sc-30555 Slk19p (yF-17) 200 ug/ml Store at 4° C,
sc-30555 P Slk19p (yF-17) P 100 ug/0.5 ml Store at 4° C,
sc-30557 Rpd3 (dN-12) 200 ug/ml Store at 4° C,
sc-30557 P Rpd3 (dN-12) P 100 ug/0.5 ml Store at 4° C,
sc-30558 Rpd3 (dI-12) 200 ug/ml Store at 4° C,
sc-30558 P Rpd3 (dI-12) P 100 ug/0.5 ml Store at 4° C,
sc-30559 Rpd3 (dV-13) 200 ug/ml Store at 4° C,
sc-30559 P Rpd3 (dV-13) P 100 ug/0.5 ml Store at 4° C,
sc-30560 SR-3 (S-19) 200 ug/ml Store at 4° C,
sc-30560 P SR-3 (S-19) P 100 ug/0.5 ml Store at 4° C,
sc-30566 Rad50 (yQ-20) 200 ug/ml Store at 4° C,
sc-30566 P Rad50 (yQ-20) P 100 ug/0.5 ml Store at 4° C,
sc-30568 Rad54 (yK-21) 200 ug/ml Store at 4° C,
sc-30568 P Rad54 (yK-21) P 100 ug/0.5 ml Store at 4° C,
sc-30570 Rad54 (yC-16) 200 ug/ml Store at 4° C,
sc-30570 P Rad54 (yC-16) P 100 ug/0.5 ml Store at 4° C,
sc-30572 OPA1 (V-20) 200 ug/ml Store at 4° C,
sc-30572 P OPA1 (V-20) P 100 ug/0.5 ml Store at 4° C,
sc-30573 OPA1 (C-15) 200 ug/ml Store at 4° C,
sc-30573 P OPA1 (C-15) P 100 ug/0.5 ml Store at 4° C,
sc-30578 Thimet oligopeptidase (Q-17) 200 ug/ml Store at 4° C,
sc-30578 P Thimet oligopeptidase P 100 ug/0.5 ml Store at 4° C,
sc-30579 Thimet oligopeptidase (E-17) 200 ug/ml Store at 4° C,
sc-30579 P Thimet oligopeptidase P 100 ug/0.5 ml Store at 4° C,
sc-30581 Isw1p (yS-15) 200 ug/ml Store at 4° C,
sc-30581 P Isw1p (yS-15) P 100 ug/0.5 ml Store at 4° C,
sc-30588 NTE (C-20) 200 ug/ml Store at 4° C,
sc-30588 P NTE (C-20) P 100 ug/0.5 ml Store at 4° C,
sc-30589 DSCR1 (N-20) 200 ug/ml Store at 4° C,
sc-30589 P DSCR1 (N-20) P 100 ug/0.5 ml Store at 4° C,
sc-30594 ADX Reductase (P-15) 200 ug/ml Store at 4° C,
sc-30594 P ADX Reductase (P-15) P 100 ug/0.5 ml Store at 4° C,
sc-30595 ADX Reductase (C-15) 200 ug/ml Store at 4° C,
sc-30595 P ADX Reductase (C-15) P 100 ug/0.5 ml Store at 4° C,
sc-30596 ATF-6∫ (N-17) 200 ug/ml Store at 4° C,
sc-30596 P ATF-6∫ (N-17) P 100 ug/0.5 ml Store at 4° C,
sc-30597 ATF-6∫ (E-14) 200 ug/ml Store at 4° C,
sc-30597 P ATF-6∫ (E-14) P 100 ug/0.5 ml Store at 4° C,
sc-30601 BCAP (S-15) 200 ug/ml Store at 4° C,
sc-30601 P BCAP (S-15) P 100 ug/0.5 ml Store at 4° C,
sc-30602 Dysadherin (N-20) 200 ug/ml Store at 4° C,
sc-30602 P Dysadherin (N-20) P 100 ug/0.5 ml Store at 4° C,
sc-30603 Dysadherin 2 (L-15) 200 ug/ml Store at 4° C,
sc-30603 P Dysadherin 2 (L-15) P 100 ug/0.5 ml Store at 4° C,
sc-30606 Dysadherin (P-17) 200 ug/ml Store at 4° C,
sc-30606 P Dysadherin (P-17) P 100 ug/0.5 ml Store at 4° C,
sc-30612 CYP3A (D-17) 200 ug/ml Store at 4° C,
sc-30612 P CYP3A (D-17) P 100 ug/0.5 ml Store at 4° C,
sc-30613 CYP3A (K-18) 200 ug/ml Store at 4° C,
sc-30613 P CYP3A (K-18) P 100 ug/0.5 ml Store at 4° C,
sc-30621 CYP3A (L-14) 200 ug/ml Store at 4° C,
sc-30621 P CYP3A (L-14) P 100 ug/0.5 ml Store at 4° C,
sc-30622 PARP-2 (A-18) 200 ug/ml Store at 4° C,
sc-30622 P PARP-2 (A-18) P 100 ug/0.5 ml Store at 4° C,
sc-30624 PARP-2 (T-13) 200 ug/ml Store at 4° C,
sc-30624 P PARP-2 (T-13) P 100 ug/0.5 ml Store at 4° C,
sc-30625 PARP-3 (N-13) 200 ug/ml Store at 4° C,
sc-30625 P PARP-3 (N-13) P 100 ug/0.5 ml Store at 4° C,
sc-30631 MYH (A-13) 200 ug/ml Store at 4° C,
sc-30631 P MYH (A-13) P 100 ug/0.5 ml Store at 4° C,
sc-30633 MYH (M-15) 200 ug/ml Store at 4° C,
sc-30633 P MYH (M-15) P 100 ug/0.5 ml Store at 4° C,
sc-30635 P p-MEK-1 (Ser 298) P 100 ug/0.5 ml Store at 4° C,
sc-30635-R p-MEK-1 (Ser 298)-R  200 ug/ml Store at 4° C,
sc-30640 syncytin (K-12) 200 ug/ml Store at 4° C,
sc-30640 P syncytin (K-12) P 100 ug/0.5 ml Store at 4° C,
sc-30645 PYPAF (N-13) 200 ug/ml Store at 4° C,
sc-30645 P PYPAF (N-13) P 100 ug/0.5 ml Store at 4° C,
sc-30647 PYPAF (C-12) 200 ug/ml Store at 4° C,
sc-30647 P PYPAF (C-12) P 100 ug/0.5 ml Store at 4° C,