分类目录归档：Molecular Dimensions

Molecular Dimensions系列Structure screen 1 MD1-01列表

发表于由

产品名称

货号

产品名称

货号
The Durham pH Screen MD1-101 Memgold MD1-39
The Durham Salt Screen MD1-102 Memgold 2 MD1-63
Structure screen 1

MD1-01

 MemGold Combo value pack MD1-74
Structure screen 2

MD1-02

 Memgoldmeso MD1-114
Structure screen combination MD1-03 MemStart kit MD1-21
Stura footprint screen combination MD1-05 MemSys MD1-25
3D structure screen MD1-13 Membrance protein combination MD1-04
PACT premier MD1-29 MemChannel MD1-110
JCSG plus MD1-37 MemTrans MD1-112
Super2 combo value pack MD1-75 MemPlus™ MD1-44
Morpheus MD1-46 Lipidic-sponge phase screen MD1-48
The PGA Screen MD1-50 SelenoMethionine MD12-501
MacroSol   MD1-22 Starter pack MD11-88
ProPlex MD1-38 Sample holder MD11-87
MIDASplus MD1-106 Film sandwich MD11-82
Printed lower evaporation cover MD11-83 Lid MD11-85
Evaporation cover MD11-84 Frame MD11-56
Scalpel MD9-30

Molecular Dimensions Ltd. was founded in 1998 to provide crystallographers in the UK and Europe with products tailored to meet their specific demands from a local source. During these early days Molecular Dimensions formed some very strong alliances with leading crystallographers to develop and commercialise numerous unique ideas. Today these alliances are just as strong with our new crystalisation screen, MorpheusTM, being the latest example (MRC Laboratory of Molecular Biology, Cambridge, UK).

上海金畔生物代理Molecular Dimensions品牌蛋白结晶试剂耗材，欢迎新老客户访问Molecular Dimensions官网或者咨询我们获取更多产品信息。

Molecular Dimensions MD1-02 Structure Screen 2

发表于由

产品名称

货号

产品名称

货号
The Durham pH Screen MD1-101 Memgold MD1-39
The Durham Salt Screen MD1-102 Memgold 2 MD1-63
Structure screen 1

MD1-01

 MemGold Combo value pack MD1-74
Structure screen 2

MD1-02

 Memgoldmeso MD1-114
Structure screen combination MD1-03 MemStart kit MD1-21
Stura footprint screen combination MD1-05 MemSys MD1-25
3D structure screen MD1-13 Membrance protein combination MD1-04
PACT premier MD1-29 MemChannel MD1-110
JCSG plus MD1-37 MemTrans MD1-112
Super2 combo value pack MD1-75 MemPlus™ MD1-44
Morpheus MD1-46 Lipidic-sponge phase screen MD1-48
The PGA Screen MD1-50 SelenoMethionine MD12-501
MacroSol   MD1-22 Starter pack MD11-88
ProPlex MD1-38 Sample holder MD11-87
MIDASplus MD1-106 Film sandwich MD11-82
Printed lower evaporation cover MD11-83 Lid MD11-85
Evaporation cover MD11-84 Frame MD11-56
Scalpel MD9-30

Molecular Dimensions Ltd. was founded in 1998 to provide crystallographers in the UK and Europe with products tailored to meet their specific demands from a local source. During these early days Molecular Dimensions formed some very strong alliances with leading crystallographers to develop and commercialise numerous unique ideas. Today these alliances are just as strong with our new crystalisation screen, MorpheusTM, being the latest example (MRC Laboratory of Molecular Biology, Cambridge, UK).

上海金畔生物代理Molecular Dimensions品牌蛋白结晶试剂耗材，欢迎新老客户访问Molecular Dimensions官网或者咨询我们获取更多产品信息。

Molecular Dimensions常卖蛋白结晶试剂与耗材列表

发表于由

产品名称

货号

产品名称

货号
The Durham pH Screen MD1-101 Memgold MD1-39
The Durham Salt Screen MD1-102 Memgold 2 MD1-63
Structure screen 1

MD1-01

 MemGold Combo value pack MD1-74
Structure screen 2

MD1-02

 Memgoldmeso MD1-114
Structure screen combination MD1-03 MemStart kit MD1-21
Stura footprint screen combination MD1-05 MemSys MD1-25
3D structure screen MD1-13 Membrance protein combination MD1-04
PACT premier MD1-29 MemChannel MD1-110
JCSG plus MD1-37 MemTrans MD1-112
Super2 combo value pack MD1-75 MemPlus™ MD1-44
Morpheus MD1-46 Lipidic-sponge phase screen MD1-48
The PGA Screen MD1-50 SelenoMethionine MD12-501
MacroSol   MD1-22 Starter pack MD11-88
ProPlex MD1-38 Sample holder MD11-87
MIDASplus MD1-106 Film sandwich MD11-82
Printed lower evaporation cover MD11-83 Lid MD11-85
Evaporation cover MD11-84 Frame MD11-56
Scalpel MD9-30

Molecular Dimensions Ltd. was founded in 1998 to provide crystallographers in the UK and Europe with products tailored to meet their specific demands from a local source. During these early days Molecular Dimensions formed some very strong alliances with leading crystallographers to develop and commercialise numerous unique ideas. Today these alliances are just as strong with our new crystalisation screen, MorpheusTM, being the latest example (MRC Laboratory of Molecular Biology, Cambridge, UK).

上海金畔生物代理Molecular Dimensions品牌蛋白结晶试剂耗材，欢迎新老客户访问Molecular Dimensions官网或者咨询我们获取更多产品信息。

晶体生长试剂MD1-14-ECO,MD1-16-ECO,MD蛋白结晶代理

发表于由

两个免费的6 × 4矩阵屏幕由Dr. A.M.开发来自约克大学结构生物学实验室的Brzozowski和J. Walton说。明确策略屏幕的目的是提供一个更个性化和可选择的方法结晶问题。它们是MRC-LMB剑桥自动化战略的一部分，并被我们的许多客户广泛使用。

最初，这些筛选在许多蛋白质上进行了测试，这些蛋白质以前没有结晶，并产生了衍射质量的晶体。这些是我们最受欢迎的产品。每个筛含有24个原液和以下1M缓冲液:醋酸钠pH值4.5;醋酸钠pH 5.5;羧酸钠pH 6.5;Tris pH 7.5;Tris pH为8.5。

Product # Product Name Unit Size Unit Price
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 MD1-14 Clear Strategy™ Screen I 24 x 10 ml
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 MD1-14-ECO Clear Strategy™ I Eco Screen 24 x 10 ml  
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 MD1-15 Clear Strategy™ Screen II 24 x 10 ml  
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 MD1-15-ECO Clear Strategy™ II Eco Screen 24 X 10 ml  
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 MD1-16 The Clear Strategy™ Combination 48 x 10 mL  
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 MD1-16-ECO The Clear Strategy™ Combination Eco Screen 48 x 10 ml  
MD1-16LMB Clear Strategy™ Screen Combination pH Premixed
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 MD1-31 Clear Strategy™ Screen I HT-96 96 x 1 ml  
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 MD1-31-ECO Clear Strategy™ I HT-96 Eco Screen 96 x 1 ml  
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 MD1-32 Clear Strategy™ Screen II HT-96 96 x 1 ml  
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 MD1-32-ECO Clear Strategy™ II HT-96 Eco Screen 96 x 1 ml  
MDSR-14- Clear Strategy™ Screen I Single Reagent 100 ml  
MDSR-14-ECO- Clear Strategy™ Screen I Eco Single Reagent 100 ml  
MDSR-15- Clear Strategy™ Screen II Single Reagent 100 ml  
MDSR-15-ECO- Clear Strategy™ Screen II Eco Single Reagent 100 ml  
MDSR-31 Clear Strategy™ Screen I HT-96 Single Reagent Clear Strategy™ Screen I HT-96 Single Reagent 100 ml
MDSR-31-ECO- Clear Strategy™ Eco Screen I HT-96 Single Reagent 100 ml  
MDSR-32- Clear Strategy™ Screen II HT-96 Single Reagent 100 ml  
MDSR-32-ECO- Clear Strategy™ Eco Screen II HT-96 Single Reagent 100 ml

The BCS Screen MD1-104-ECO,MD2-250-259,MD代理

发表于由

The BCS (Basic Chemical Space) Screen developed at the Structural Genomic Consortium (SGC), Oxford has a novel approach to screening. PEGs are grouped by molecular weight and mixed to create four PEG Smears* (available to purchase separately). The Smears cover a broader range of chemical space while reducing the number of PEG variables. The benefit of using PEG smears is that it reduces the number of PEG variables while maintaining a large coverage of PEG space.

The bottom line is that in tests at the SGC with 191 human proteins, the BCS Screen had a 42% hit rate with only 96 conditions. Many of these proteins had failed to crystallize in other screens.

PEG Smears for broader chemical space coverage

牛津大学结构基因组联盟(SGC)开发的BCS(基本化学空间)筛选有一种新颖的筛选方法。PEG按分子量分组并混合以创建四个PEG涂片*(可单独购买)。涂片覆盖了更广泛的化学空间，同时减少了PEG变量的数量。使用PEG涂片的好处是，它减少了PEG变量的数量，同时保持了较大的PEG空间覆盖率。

底线是，在SGC对191种人类蛋白质的测试中，BCS筛选在仅96种条件下的命中率为42%。这些蛋白质中有许多在其他筛选中无法结晶。

Product # Product Name Unit Size Unit Price
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 MD1-104 The BCS Screen 96 x 10 ml  
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 MD1-104-ECO The BCS Eco Screen 96 x 10 ml  
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 MD1-105 The BCS Screen HT-96 96 x 1 ml
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 MD1-105-ECO The BCS Screen HT-96 Eco Screen 96 x 1 ml
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 MD1-105-FX The BCS Screen FX pre-filled plate 96 x 100 µl
MD2-100-258 50% v/v PEG Smear Low (100ml) 100 ml  
MD2-100-259 50% v/v PEG Smear Medium (100ml) 100 ml  
MD2-100-260 50% v/v PEG Smear High (100ml) 100 ml
MD2-100-261 50% v/v PEG Smear Broad (100ml) 100 ml  
MD2-250-258 50% v/v PEG Smear Low (250ml) 250 ml
MD2-250-259 50% v/v PEG Smear Medium (250ml) 250 ml  
MD2-250-260 50% v/v PEG Smear High (250ml) 250 ml  
MD2-250-261 50% v/v PEG Smear Broad (250ml) 250 ml
MDSR-104- The BCS Screen Single Reagent 100 ml
MDSR-104-ECO- The BCS Eco Screen Single Reagent 100 ml  
MDSR-105- The BCS Screen HT-96 Single Reagent 100 ml
MDSR-105-ECO- The BCS Eco Screen HT-96 Single Reagent 100 ml

3D Structure Screen MD1-13-ECO,MD代理

发表于由

英国Molecular Dimensions  www.moleculardimensions.com
英国Molecular Dimensions欧洲权威蛋白质结晶试剂与耗材生产商

Product # Product Name Unit Size Unit Price
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 MD1-13 3D Structure Screen 48 x 10 mL  
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 MD1-13-ECO 3D Structure Eco Screen 48 x 10 mL  
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 MD1-35 Heavy + Light (3D Structure Screen) Twin Pack HT-96 48 x 1 mL (x 2)  
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 MD1-35-ECO Heavy + Light (3D Structure Screen) Twin Pack HT-96 Eco Screen 48 x 1 ml (x 2)  
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 MD1-35-FX Heavy + Light (3D Structure Screen) Twin Pack FX-96 pre-filled plate 48 x 100 µL (x 2)  
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 MDSR-13- 3D Structure Screen Single Reagent 100 ml  
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 MDSR-13-ECO- 3D Structure Screen Eco Single Reagent 100 ml  
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 MDSR-35- Heavy + Light (3D Structure Screen) Twin Pack HT-96 Single Reagent 100 ml  
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 MDSR-35-ECO- Heavy + Light (3D Structure Screen) Twin Pack HT-96 Eco Single Reagent 100 ml

The 3D Structure Screen is formulated for growing protein crystals in the metastable zone using the vapour diffusion technique.

This method is presented in the 3D Structure Screen as an optimized sparse matrix crystal growth screen which allows the 24 “nucleation” conditions of the Mini Screen and 24 “backed-off” conditions for crystal growth to be tried. Formatted for HT blocks as the Heavy + Light (3D Structure Screen) Twin Pack HT-96.

Features of 3D Structure Screen:

  • Separate nucleation from crystal growth.
  • A simple method for growing crystals in the metastable zone.
  • Obtain much larger and better diffracting crystals compared to conventional methods.

MD15-C12-B,MD1-61-ECO蛋白结晶试剂耗材,Molecular Dimensions代理

发表于由

适合冷冻保护晶体的屏幕。CryoProtX和CryoSol在晶体生长后提供低温保护。这些屏幕中的冷冻保护剂稳定了结晶状态，防止在闪冷过程中结冰。CryoSol还提供了一套扩展的多组分解决方案，用于晶体冷冻保护和将疏水配体浸泡成晶体。向导冷冻线提供稀疏基质筛选与节省使用甘油。

Molecular Dimensions产品列表

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MD15-C12-BWizard Cryo 1&2 HT9696 x 1.7 ml

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MD15-C12-TWizard Cryo 1 & 2 (10mL)96 x 10 ml

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MD15-C1-TWizard Cryo 1 (10mL)48 x 10 ml

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MD15-C2-TWizard Cryo 2 (10mL)48 x 10 ml

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MD1-61CryoProtX™46 x 1.5 ml

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MD1-61-ECOCryoProtX™ Eco Screen46 x 1.5 ml

MD1-90CryoSol™33 x 1.5 ml

MD1-94The Cryo Combination(33 x 1.5 ml + 46 x 1.5 ml)

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MDSR-61-CryoProtX™ Single Reagent1.5 ml

MDSR-61-ECO-CryoProtX™ Mix Eco Screen Single Reagent1.5 ml

Additive Screens MD1-100-FX,MD1-71,蛋白结晶试剂耗材Molecular Dimensions代理

发表于由

通过添加底物类似物、抑制剂、配体或其他添加剂，可以进一步改善晶体。加性筛选对于小/衍射差的晶体或太多的成核是有用的。

可以采取多种方法:

使用我们的任何添加剂筛(用于可溶性或膜蛋白)-使用您的hit条件作为基础。
在你最初的目标中寻找共同的化学实体。使用此实体作为添加剂，对一个或多个主屏幕进行重新筛选。
如果已知你的蛋白质与配体结合，使用配体作为添加剂，用一个或多个初级筛选重新筛选。
执行热荧光实验，测试您的蛋白质与添加屏幕。如果你观察到你的蛋白质有显著的稳定性，使用稳定条件作为添加剂，用一个或多个主筛重新筛选。

Product # Product Name Unit Size Unit Price
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 MD1-100 The ANGSTROM Additive Screen™ 96 x 1 ml  
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 MD1-100-FX The ANGSTROM Additive Screen™ FX-96 96 x 100 µl  
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 MD1-109 Calixar C2B 10 x 50 µl  
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 MD1-11 Additive Screen 24 x 100 µl  
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 MD1-118 Hippocrates 48 x 100 µl  
MD1-70 MemAdvantage™ (0.25 mL) 96 x 0.25 ml  
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 MD1-71 MemAdvantage™ (1 mL) 96 x 1 ml  
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 MD1-93 The Morpheus® Additive Screen 96 x 100 µl  
MDSR-100- Angstrom Additive Screen HT-96 single reagent 100 ml

Cover Slips,24-Well Plates,Molecular Dimensions代理蛋白结晶试剂耗材

发表于由

硅化(或更准确地说硅化)玻璃盖卡瓦通常用于设置吊滴蒸汽扩散实验。虽然非常适合这种技术，但制造商发现很难定期获得清洁的玻璃原料。一种受欢迎的硅化玻璃替代品是一种干净且光学透明的塑料。Molecular Dimensions提供这种材料的盖片，名称为CrystalClene卡瓦。这些盖卡瓦不需要硅化，保证清洁，无尘，无RNase。另一个优点是它们坚不可摧。

CleneGlass™盖玻片

清洁，德国玻璃盖子，普通或硅化，用于挂滴实验。

CrystalClene™滑落

牢不可破的聚碳酸酯盖，用于悬挂跌落实验。保证干净的聚碳酸酯盖为悬挂滴。虽然塑料盖盖已经使用了一段时间，但Molecular Dimensions公司推出的这些聚碳酸酯盖盖标志着悬滴结晶盖盖技术的巨大进步。

Product # Product Name Unit Size Unit Price
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 MD4-02 Siliconised 18mm round cover slips 1000  
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 MD4-04 Siliconised 22mm round cover slips 1000  
MD4-06 Siliconised 22mm square cover slips 2000  
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 MD4-07 18mm round cover slips (plain) 1000  
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 MD4-08 22mm round cover slips (plain) 1000  
MD4-09 22mm square cover slips (plain) 1000  
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 MD4-10 CrystalClene Slips 22mm Square 100 100  
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 MD4-11 CrystalClene Slips 22mm Square 1000 1000  
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 MD4-12 CrystalClene Slips 18mm round 100  
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 MD4-13 CrystalClene Slips 18mm round 1000 1000  
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 MD4-14 CrystalClene Slips 22mm round 100  
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 MD4-15 CrystalClene Slips 22mm round 1000  
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 MD4-16 CrystalClene Slips 18mm Square 100 100  
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 MD4-17 CrystalClene Slips 18mm Square 1000 1000  
MD4-18 18mm round cover slips (No. 3) (plain) 1000  
MD4-19 22mm round cover slips (No. 3) (plain) 1000  
MD6-02 Sealing Grease 50 g  
MD6-07 Canned Air (400ml) 1

Molecular Dimensions代理,MD3-11T,MD6-02产品列表

发表于由

建立结晶试验的传统选择是24孔林布罗式板，这实际上是一种过时的组织培养板。该板的主要优点是井距足够大，可以在涂有润滑油的井缘上下操作盖卡瓦。凸起的盖子设计，如XRL板，避免了需要在角落使用橡皮泥(造型粘土)，以防止盖子压碎盖卡瓦。这些板可用于带盖卡瓦的挂滴蒸汽扩散和带桥的坐滴。这是手工使用和优化的标准板。

A classic 24-Well “Linbro” style plate with a raised lid.
XRL™ Plate

Product # Product Name Unit Size Unit Price Quantity
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 MD3-11 24-well XRL Plate (100) 100  
MD3-11T XRL Plate trial pack with CrystalClene Slips 40 + 1000  
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 MD3-16 Greiner 24 well Combo Plate (SBS format) with lid 1  
MD3-17 Sitting Drop Bridges 100
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 MD3-21 Greiner pre-greased 24 well Combo Plate (SBS format) with lid 1  
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 MD6-02 Sealing Grease 50 g

上海金畔生物代理Molecular Dimensions品牌蛋白结晶试剂耗材工具等，我们将竭诚为您服务，欢迎访问Molecular Dimensions官网或者咨询我们获取更多相关Molecular Dimensions品牌产品信息。