JBScreen pH-2D allows sampling of a broad pH range without changing the buffering environment [1]. This ensures that pH screening is independent of the chemical nature of the components of the buffer system.JBScreen pH-2D contains six extended range buffer systems, each composed of a mixture of three individual buffers with a distinct chemical nature and well separated pKa values. Each buffer system is composed of a low-pH and a high-pH stock solution, supplied in 10 ml volumes. The low-pH stock solution is preset at pH 4.0 and the high-pH solution at either pH 9.0 or 10.0 (see download). Thus, mixtures of the low-pH and high-pH stock solutions in different proportions provide coverage of the entire pH range from 4.0 – 9.0 or 4.0 – 10.0, respectively. The composition of the buffer systems assures a virtually linear distribution of the resulting pH vs the percentage of high pH / low pH stock.

Larger volumes are available upon request.

[1] Newman (2004) Novel buffer systems for macromolecular crystallization. Acta Cryst. D60:610.

Note: This is a special order item with 2-4 weeks delivery , during our initial phase of carrying Jena products. If you would like us to stock this item, please let us know!

Download technical sheet from below:JBScreen pH-2D

SKU： M-CS-701类别： 结晶优化
产品信息
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产品规格
JBScreen pH-2D 允许在不改变缓冲环境的情况下对广泛的 pH 范围进行采样 [1]。这确保了 pH 筛选与缓冲系统组分的化学性质无关。
JBScreen pH-2D 包含六个扩展范围的缓冲系统，每个系统由三种具有独特化学性质和分离良好的 pKa 值的单独缓冲液的混合物组成。每个缓冲系统由低 pH 和高 pH 储备溶液组成，以 10 毫升体积提供。低 pH 储备溶液预设为 pH 4.0，高 pH 溶液预设为 pH 9.0 或 10.0（参见下载）。因此，不同比例的低 pH 和高 pH 储备溶液的混合物分别提供了 4.0 – 9.0 或 4.0 – 10.0 的整个 pH 范围的覆盖范围。缓冲系统的组成确保所得 pH 值与高 pH 值/低 pH 值储备的百分比几乎呈线性分布。

可根据要求提供更大的体积。

[1] Newman (2004) 用于大分子结晶的新型缓冲系统。晶体学报。 D60：610。

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JBScreen pH-2D